However, these medications may need to be taken or applied for at least three months. Fungal nails can be painful, even in mild cases or without underlying conditions. The suitability of any of the described options in an individual case can be determined by talking to a doctor. Raleigh Foot & Ankle Center provides services to patients throughout North Carolina. Toenail fungus can be caused by several factors. Traditional herbalists used it to heal sore throats and wounds. It also works well targeting interests like weight loss, fitness, conservativism, blood pressure, and ED.